Ribavirin Online



How and where to order Ribavirin (Copegus, Rebetol) 100 mg, 200 mg capsules and tablets online on Autoimmune Information Network, Inc. website:

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Prices:from $0.95 per pill
Discount:10% coupon: MSD10
Forms:Ribavirin 100 mg, 200 mg tablets and capsules
Quantity:10-280 pills
Type:Ribavirin brand, Copegus generic, Rebetol generic
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Delivery:Regular and express mail service
Shipping:Worldwide, including USA, UK, Europe, Canada, Australia


Ribavirin (trade names include Copegus, Rebetol, Moderiba, Ribasphere, Ribavin, Ribavirin Teva, Ribazole, Vilona, Viramid, Virazide, Virazole) is an antiviral medication from nucleosides and nucleotides pharmacological group. This medicine is used for the treatment of viral infections, such as chronic hepatitis C, respiratory syncytial virus (RSV), viral hemorrhagic fever infections (Crimean-Congo hemorrhagic fever, Lassa fever, Venezuelan hemorrhagic fever, Hantavirus infection), herpes simplex virus, rabies, canine distemper, cancers, acute myeloid leukemia, and related diseases. It works as guanosine (ribonucleic) analog and nucleoside inhibitor. Rebetol and Copegus stop viral RNA synthesis and viral replication. Ribavirin can be used alone or in combinations with interferon, peginterferon, and other antiviral drugs.


Copegus, Rebetol (Ribavirin)


Related medications:

  • Acyclovir (Zovirax)
  • Amantadine (Symmetrel)
  • Brivudine (Zostex)
  • Cefpodoxime (Vantin)
  • Cidofovir (Vistide)
  • Clofazimine (Lamprene)
  • Daclatasvir (Daklinza)
  • Disoproxil Fumarate, Tenofovir (Viread)
  • Efavirenz (Sustiva)
  • Efavirenz, Emtricitabine, Tenofovir (Atripla)
  • Emtricitabine, Tenofovir (Truvada)
  • Famciclovir (Famvir)
  • Ganciclovir (Zirgan)
  • Idoxuridine (Dendrid)
  • Indinavir (Crixivan)
  • Lamivudine (Epivir)
  • Lamivudine, Zidovudine (Combivir)
  • Penciclovir (Denavir)
  • Providone-Iodine (Betadine)
  • Valacyclovir (Valtrex)
  • Valganciclovir (Valcyte)
  • Vidarabine (Vira-A)
  • Zidovudine (Retrovir)


    Pharmacological and medical categories:

  • Agents to treat autoimmune diseases
  • Anti herpes medicines
  • Anti rabies pills
  • Anticancer drugs
  • Antivirals
  • Medications for the treatment of fevers
  • Nucleoside analogues
  • Nucleotides


    ATC codes:

  • J - Antiinfectives for systemic use
  • J05 - Antivirals for systemic use
  • J05A - Direct acting antivirals
  • J05AP - Antivirals for treatment of HCV infections
  • J05AP01 - Ribavirin


    ICD-10 codes:

  • Rabies - A82
  • Rabies, unspecified - A82.9
  • Other mosquito-borne viral fevers - A92
  • Venezuelan equine fever - A92.2
  • Arenaviral hemorrhagic fever - A96
  • Lassa fever - A96.2
  • Other viral hemorrhagic fevers, not elsewhere classified - A98
  • Crimean-Congo hemorrhagic fever - A98.0
  • Unspecified viral hemorrhagic fever - A99
  • Herpesviral [herpes simplex] infections - B00
  • Herpes simplex myelitis - B00.82
  • Chronic viral hepatitis - B18
  • Chronic viral hepatitis C - B18.2
  • Other viral diseases, not elsewhere classified - B33
  • Hantavirus (cardio)-pulmonary syndrome [HPS] [HCPS] - B33.4
  • Viral agents as the cause of diseases classified elsewhere - B97
  • Respiratory syncytial virus as the cause of diseases classified elsewhere - B97.4
  • Neoplasms - C00-D49
  • Myeloid leukemia - C92
  • Contact with dog - W54


    Indications and usage:

    Ribavirin (Copegus, Rebetol) is a nucleoside analogue indicated in combination with interferon alfa-2b (pegylated and nonpegylated) for the treatment of Chronic Hepatitis C (CHC) in patients 3 years of age or older with compensated liver disease.

    Patients with the following characteristics are less likely to benefit from re-treatment after failing a course of therapy: previous nonresponse, previous pegylated interferon treatment, significant bridging fibrosis or cirrhosis, and genotype 1 infection.


    Dosage and administration:

    Ribavirin is administered according to body weight.
    Dose reduction or discontinuation is recommended in patients experiencing certain adverse reactions or renal dysfunction.


    Dosage forms and strengt:

  • Copegus (Ribavirin) tablets 100 mg, 200 mg.
  • Rebetol (Ribavirin) capsules 200 mg.
  • Rebetol (Ribavirin) oral solution 40 mg per mL.


    Overdosage:

    There is limited experience with overdosage. Acute ingestion of up to 20 g of ribavirin capsules, Intron A ingestion of up to 120 million units, and subcutaneous doses of INTRON A up to 10 times the recommended doses have been reported. Primary effects that have been observed are increased incidence and severity of the adverse reactions related to the therapeutic use of Intron A and Ribavirin (Copegus, Rebetol). However, hepatic enzyme abnormalities, renal failure, hemorrhage, and myocardial infarction have been reported with administration of single subcutaneous doses of Intron A that exceed dosing recommendations.

    There is no specific antidote for Intron A or ribavirin overdose, and hemodialysis and peritoneal dialysis are not effective for treatment of overdose of these agents.


    Contraindications:

  • Pregnancy and men whose female partners are pregnant
  • Known hypersensitivity reactions such as Stevens-Johnson syndrome, toxic, epidermal necrolysis, and erythema multiforme to ribavirin or any component of the product
  • Autoimmune hepatitis
  • Hemoglobinopathies
  • Creatinine clearance less than 50 mL/min
  • Coadministration of ribavirin with didanosine


    Warnings and precautions:

  • Embryo-fetal toxicity: may cause fetal harm. Patients should have a negative pregnancy test prior to therapy and use effective contraception and undergo periodic pregnancy tests.

    Patients exhibiting the following conditions should be closely monitored and may require dose reduction or discontinuation of therapy:
  • Hemolytic anemia may occur with a significant initial drop in hemoglobin.
  • Pancreatitis.
  • Pulmonary infiltrates or pulmonary function impairment.
  • New or worsening ophthalmologic disorders.
  • Severe decreases in neutrophil and platelet counts, and hematologic, endocrine (e.g., TSH), and hepatic abnormalities.
  • Dental/periodontal disorders reported with combination therapy.
  • Concomitant administration of azathioprine.
  • Weight loss and growth inhibition reported during combination therapy in pediatric patients. Long-term growth inhibition (height) reported in some patients.
  • Monotherapy with ribavirin is not permitted.


    Adverse reactions, side effects:

    Hemolytic anemia occurred in more than 10% of adult patients receiving Rebetol/PegIntron or Intron A combination therapy.

    Most common adverse reactions (40% or greater) in adult patients receiving Copegus or Rebetol/PegIntron or Intron A combination therapy are injection site reaction, fatigue/asthenia, headache, rigors, fevers, nausea, myalgia and anxiety/emotional lability/irritability. Most common adverse reactions (greater than 25%) in pediatric patients receiving Rebetol/PegIntron therapy are: pyrexia, headache, neutropenia, fatigue, anorexia, injection site erythema, and vomiting.

    To report suspected side effects of Copegus or Rebetol (Ribavirin) capsules and tablets contact Roche and Merck pharmaceutical companies, or your local FDA.


    Drug interactions:

    Nucleoside analogues: closely monitor for toxicities. Discontinue nucleoside reverse transcriptase inhibitors or reduce dose or discontinue interferon, ribavirin or both with worsening toxicities.


    Use in specific populations:

  • Pediatrics: safety and efficacy in patients less than 3 years old have not been established.
  • Organ transplant recipients: safety and efficacy not studied.
  • Co-infected patients: safety and efficacy with HIV or HBV co-infection have not been established.


    Patient counseling information:

    Anemia

    The most common adverse experience occurring with Ribavirin (Copegus, Rebetol) capsules and tablets is anemia, which may be severe. Advise patients that laboratory evaluations are required prior to starting therapy and periodically thereafter. Advise patients to be well hydrated, especially during the initial stages of treatment.

    Embryo-fetal toxicity

    Inform females of reproductive potential and pregnant women that ribavirin pills and oral solution may cause birth defects, miscarriage, and stillbirth. Advise females of reproductive potential that they must have a pregnancy test prior to initiating treatment and periodically during therapy.

    Advise females of reproductive potential and male patients with female partners of reproductive potential to use effective contraception during treatment with Copegus or Rebetol and for 6 months post therapy. Advise patients to notify the physician immediately in the event of a pregnancy.

    Missed dose

    Inform patients that in the event a dose is missed, the missed dose should be taken as soon as possible during the same day. Patients should not double the next dose. Advise patients to contact their healthcare provider if they have questions.

    Dental and periodontal disorders

    Advise patients to brush their teeth thoroughly twice daily and have regular dental examinations. If vomiting occurs, advise patients to rinse out their mouth thoroughly afterwards.


    Pregnancy categories:

  • X - Australia
  • X - United States (Should not be used during pregnancy)


    Salts and other forms:

  • Ribavirin Base


    Synonyms, international and chemical names:

  • 1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-
  • 1-Beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
  • 1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-
  • Ribavirina
  • Ribavirine
  • Ribavirinum
  • RTC
  • RTCA
  • RTP
  • Tribavirin
  • Rybawiryna
  • Virazole 5'-Triphosphate


    Brands, generics, trade names:

  • Copegus - Roche
  • Desiken - Kendrick Laboratorios
  • Ibavyr - Pendopharm
  • Moderiba - AbbVie
  • Rebetol - Schering-Plough, Merck
  • Ribasphere - Three Rivers Pharmaceuticals
  • Ribasphere RibaPak Kit - Three Rivers Pharmaceuticals
  • Ribavin - Lupin Pharmaceuticals
  • Ribavirin - Arcana Arzneimittel, Cadila Healthcare, CT-Arzneimittel, Generics UK, Hexal, Mylan, Pliva, Sandoz, Teva, Zydus Pharmaceuticals
  • Ribavirina - Aurobindo, Serral, Teva
  • Ribavirine - Arrow Generics, Biogaran, Mylan, Ratiopharm, Sandoz, Teva
  • Ribazole - Getz Pharma, Fair Deal, Getz Brothers Philippines
  • Robatrol - Roche
  • Tinamous - Zephyr Pharmatec
  • Trivorin - Teva, Lemery
  • Vilona - Valeant Pharmaceuticals, ICN Pharmaceuticals
  • Vilona Pediatrica - Valeant Pharmaceuticals, ICN Pharmaceuticals
  • Viracure - Egyptian Pharmaceutical Company, October Pharma
  • Viramid - ICN Pharmaceuticals, Ilsung Pharmaceuticals
  • Viramune - Webros Pharmaceuticals
  • Virazide - Valeant Pharmaceuticals, Armoxindo Farma, Grossman Laboratorios, ICN Pharmaceuticals, Lupin Pharmaceuticals, Novartis, Pharmedic Laboratories, Pinnacle CVS
  • Virazide Pediatrico - Valeant Pharmaceuticals, Grossman Laboratorios, ICN Pharmaceuticals, Novartis
  • Virazole - Valeant Pharmaceuticals
  • Virocid - Ostin Pharmaceutical
  • Xilopar - Filaxis Laboratorios
  • Xolox - Ferozsons Laboratoies


    APIs used in medicine in combinations with ribavirin:

  • Boceprevir
  • Interferon Alfa-2a
  • Interferon Alfa-2b
  • Interferon Alfa-2b Human recombinant
  • Interferon Alfa-2b recombinant
  • Peginterferon Alfa-2a
  • Peginterferon Alfa-2b
  • Simeprevir
  • Sofosbuvir
  • Vitamins


    Here is a list of popular medications containing ribavirin as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Copegus
  • Tablets, Film-Coated; Oral; Ribavirin 200 mg
  • Tablets, Film-Coated; Oral; Ribavirin 400 mg
  • Roche
  • Chugai Pharmaceutical
  • Delphi Pharmaceuticals
  • DKSH
  • Emra-Med Arzneimittel
  • G.A. Stamatis & Co.
  • Genentech
  • Haemato Pharm
  • Orifarm
  • Patheon
  • Rebetol
  • Capsules; Oral; Ribavirin 200 mg
  • Solution; Oral; Ribavirin 40 mg / ml
  • Schering-Plough
  • Aesca
  • Agencia Lei Va Hong
  • Bayer Schering Pharma
  • Essex
  • Fulford Pharmaceuticals
  • Merck
  • Pfizer
  • Trading Pharma
  • Zuellig Pharma
  • Ribasphere
  • Capsules; Oral; Ribavirin 200 mg
  • Tablets, Film-Coated; Oral; Ribavirin 200 mg
  • Tablets, Film-Coated; Oral; Ribavirin 400 mg
  • Tablets, Film-Coated; Oral; Ribavirin 600 mg
  • Three Rivers Pharmaceuticals
  • Biomeks Ilac
  • DSM Pharmaceuticals
  • Kadmon
  • Ribavin
  • Capsules; Oral; Ribavirin 100 mg
  • Capsules; Oral; Ribavirin 200 mg
  • Syrup; Oral; Ribavirin 50 mg / 5 ml
  • Lupin Pharmaceuticals
  • Pinnacle CVS
  • Virazole
  • Injectable; Infusion; Ribavirin 100 mg / ml
  • Powder for Solution; Inhalation; Ribavirin 6 g
  • Valeant Pharmaceuticals
  • Antigen Pharmaceuticals
  • Egyptian Pharmaceutical Company
  • Firma Chun Cheong
  • ICN Pharmaceuticals
  • IDS Group
  • Inex-Intherexport
  • Invida
  • JDH Pharmaceutical
  • Legacy Pharmaceuticals
  • Meda
  • Orphan Pharmaceutical
  • Sanico
  • Sanofi-Aventis
  • UCI-Farma Industria Farmaceutica
  • ViraTek
  • Zuellig Pharma



  • References:

  • Ribavirin main article on Wikipedia: https://en.wikipedia.org/wiki/Ribavirin
  • Ribavirin compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Ribavirin
  • Ribavirin medicine on DrugBank: https://go.drugbank.com/drugs/DB00811
  • Ribavirin FAQ on MedlinePlus (revised 06/15/2016): https://medlineplus.gov/druginfo/meds/a605018.html
  • Cadila Ribavirin tablets film coated drug label info on DailyMed (revised September 14, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Aurobindo Ribavirin tablets film coated drug label info on DailyMed (revised November 24, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Zydus Ribavirin capsules drug label info on DailyMed (revised May 15, 2019): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Rebetol (Ribavirin) capsules and liquid drug label info on DailyMed (revised December 1, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Ribavirin containing drugs on Drugs-About.com: https://drugs-about.com/ing/ribavirin.html
  • Ribavirin for sale on Pharma Doctor: https://pharma-doctor.com/ribavirin.html
  • Copegus (Ribavirin) tablets for oral use official prescribing information and medication guide from the U.S. FDA (revised 08/2015): https://www.accessdata.fda.gov/drugsatfda_docs/label...
  • Rebetol (Ribavirin USP) capsules for oral use, oral solution official prescribing information and medication guide from the U.S. FDA (revised 11/2013): https://www.accessdata.fda.gov/drugsatfda_docs/label...
  • Copegus (Ribavirin) film-coated tablets prescribing information from Roche pharmaceutical company (revised Jul 2015): https://www.roche.com.sg/content/dam/...
  • Rebetol (Ribavirin) capsules and oral solution prescribing information from Merck pharmaceutical company (revised 01/2020): https://www.merck.com/product/usa/pi_circulars/r/...
  • Virazole (Ribavirin for inhalation solution, USP) prescribing information from Bausch & Lomb (revised 05/2019): https://www.bauschhealth.com/Portals/25/Pdf/PI/Virazole-PI.pdf
  • Ribavirin 200 mg capsules package information leaflet from Medicines.org.uk (revised 09/2020): https://www.medicines.org.uk/emc/files/pil.7117.pdf

    Revised: August 2021



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